Anam Abrar ( Division of Neurology, Shifa International Hospital, Islamabad. )
Arsalan Ahmad ( Division of Neurology, Shifa International Hospital, Islamabad. )
May 2015, Volume 65, Issue 5
Author's Reply
We thank Dr Arzu Yagis On for pointing out an inadvertent error in quoting from his study1 in the discussion part of our case report. The confusion was due to a Cochrane Review on Postpolio syndrome2 that reviewed nine pharmacological and three non-pharmacological treatments for PPS. We reviewed the article by Elisabeth Farbu3 quoted by Dr On in the above letter and found that she also cited the study by On et al as an open study. This review article also concluded that the primary treatment of PPS is based on non-pharmacological interventions and lifestyle modifications.
We would like to correct the statement to read \'A single blinded randomized study found lamotrigine to be effective in relieving pain, fatigue and quality of life, but double blind randomized controlled studies are needed to establish efficacy\'.
References
1. On AY, Oncu J, Uludag B, Ertekin C. Effects of Lamotrigine on the symptoms and quality of life of patients with post polio syndrome: a randomized controlled study. Neuro Rehabilitation 2005; 20: 245-51.
2. Koopman FS, Uegaki K, Gilhus NE, Beelen A, de Visser M, Nollet F. Treatment for postpolio syndrome. Cochrane Database of Systemic Reviews 2011, Issue 2. Art No:CD007818. Page 20-21. DOI:10.1002/14651858.CD007818.pub2.
3. Farbu E. Update on current and emerging treatment options for post-polio syndrome. Therapeutics and Clinical Risk Management 2010; 6: 307-13.
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