Arzu Yagiz On ( Ege University Medical Faculty, Department of Physical Medicine and Rehabilitation, Izmir, Turkey. )
May 2015, Volume 65, Issue 5
Letter to the Editor
Madam, RE: Post poliomyelitis syndrome: A raresequel of acute poliomyelitis.1
In this case report, the authors referred to our article2 and stated that lamotrigine was found to be ineffective in post poliosyndrome in a case control study. However, there seems to be two major mistakes. 1. Our study was not a case-control study, instead a randomized controlled study. 2. In this study, we found lamotrigine to be effective in relieving pain and fatigue symptoms and improving life qualities of patients with post-polio syndrome. We have been using Lamotrigine with great success in patients with post polio syndrome for over 15 years. However, because our study was single-blinded and not placebo-controlled, a randomized controlled trial is needed to confirm the results.3
References
1. Abrar A, Ahmad A. Post poliomyelitis syndrome: A rare sequel of acute poliomyelitis. JPak Med Assoc 2015; 65: 327-9
2. On AY, Oncu J, Uludag B, Ertekin C. Effects of lamotrigine on the symptoms and life qualities of patients with post polio syndrome: a randomized, controlled study. Neuro Rehabilitation. 2005; 20:245-51.
3. Farbu E.Update on current and emerging treatment options for post-polio syndrome.TherClin Risk Manag 2010;6:307-13.
Journal of the Pakistan Medical Association has agreed to receive and publish manuscripts in accordance with the principles of the following committees:
